This outlines evidence-based strategies for diagnosing and managing ectopic pregnancy, emphasizing the combined use of transvaginal ultrasonography and serial β-hCG measurements rather than reliance on a single value. Management is guided by hemodynamic stability, with urgent surgical intervention for unstable or ruptured cases and methotrexate appropriate for selected stable patients. Expectant management may be considered in carefully monitored individuals with low, declining β-hCG levels, underscoring the importance of individualized care and close follow-up.